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Image Search Results
Journal: eLife
Article Title: PRMT5 regulates ovarian follicle development by facilitating Wt1 translation
doi: 10.7554/eLife.68930
Figure Lengend Snippet: The expression of 3β-HSD, WT1, FOXL2, CYP11A1, and SF1 in ovaries of control and Prmt5 flox/flox ;Sf1 +/cre mice at P18 was examined by immunofluorescence. In control ovaries, 3β-HSD ( A ), CYP11A1 ( C ), and SF1 ( E ) were expressed only in theca-interstitial cells (white arrowheads). In the ovaries of Prmt5 flox/flox ;Sf1 +/cre mice, 3β-HSD ( B ), CYP11A1 ( D ), and SF1 ( F ) were also detected in granulosa cells (white arrows). Compared to the intact follicle structure in control ovaries (arrowheads, G ), the follicle structure was disordered in Prmt5 flox/flox ;Sf1 +/cre ovaries (arrows, H ) as shown by Laminin expression. DAPI (blue) was used to stain the nuclei.
Article Snippet: The following primary antibodies were used: WT1 (Abcam, ab89901), FOXL2 (Abcam, ab5096), CYP11A1 (Proteintech, 13363-1-AP), SF1 (Proteintech, 18658-1-AP), and
Techniques: Expressing, Control, Immunofluorescence, Staining
Journal: eLife
Article Title: PRMT5 regulates ovarian follicle development by facilitating Wt1 translation
doi: 10.7554/eLife.68930
Figure Lengend Snippet:
Article Snippet: The following primary antibodies were used: WT1 (Abcam, ab89901), FOXL2 (Abcam, ab5096), CYP11A1 (Proteintech, 13363-1-AP), SF1 (Proteintech, 18658-1-AP), and
Techniques: Recombinant, Plasmid Preparation, Luciferase, Reporter Assay